|Portrayed by||Ryan Cutrona|
|First appearance||Long Weekend|
|Final appearance||The Arrangements|
|Wife|| Ruth Hofstadt (deceased)|
|Parent(s)||Herman Hofstadt (father)|
|Child(ren)||Betty Hofstadt, William Hofstadt|
Eugene "Gene" Hofstadt was the father of Betty Hofstadt.
Gene fought in the World War 1 and kept a helmet from a Prussian soldier he had shot in the head.
He disliked Don Draper but eventually agreed to move in with him and Betty for a short time, during which he grew especially close to Sally Draper, whom he had taught how to drive. Not long afterward he dies while waiting in line at the A&P. Although it is uncertain exactly how Gene dies, there is a strong probability that it was due to a complication of respiratory failure of some sort brought on by untreated diabetic ketoacidosis.
Betty sees visions of her father while in a dreamlike state at the hospital to give birth to her third child, whom she names Eugene Scott Draper in honor of her father. ("The Fog")